Core Plot Summary
The novel follows a freelance writer researching the atomic bomb for a book, who becomes entangled with the family of the scientist who invented it. The scientist, a detached, childlike figure, has also created a substance called ice-nine that can turn all water on Earth into a solid. After a series of absurd, tragic events involving a fictional Caribbean nation, ice-nine is accidentally released, triggering a global apocalypse. The story is framed as a retrospective, with the narrator reflecting on the meaningless of human pursuits in the face of total destruction.